首页|Benzo(a)pyrene exposure in utero exacerbates Parkinson's Disease (PD)-like alpha-synucleinopathy in A53T human alpha-synuclein transgenic mice

Benzo(a)pyrene exposure in utero exacerbates Parkinson's Disease (PD)-like alpha-synucleinopathy in A53T human alpha-synuclein transgenic mice

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Background: Previous work indicated that benzo [al pyrene (B(alpha)P) exposure in utem might adversely affect neurodevelopment and cause Parkinson's Disease (PD)-like symptoms. However, the effect of utero exposure to B (alpha)P on PD-like alpha-synucleinopathy and the mechanism under are unclear.

Benzo[a]pyreneParkinson's Disease-like alpha-synucleinopathyAlpha-synucleinMicrogliaDopaminergic neuronal loss

Xu, Weixing、Qi, Yuze、Gao, Yanjun、Quan, Huihui、Li, Qingru、Zhou, Hui、Huang, Jing

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Peking Univ, Sch Publ Hlth, Dept Occupat & Environm Hlth Sci, Beijing 100191, Peoples R China

2021

Toxicology and Applied Pharmacology

Toxicology and Applied Pharmacology

SCI
ISSN:0041-008X
年,卷(期):2021.427
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