1. Institute of Microbiology, Guangdong Academy of Sciences
2. Central South University
3. Guangdong Pharmaceutical University
4. Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Sciences
折叠
Abstract
Neocucurbols A–D (1–4) are diterpene derivatives that possess a complex 6/6/5/5/6 polycyclic ring system with a characteristic tetrahedrofuran bridge ring skeleton. Neocucurbols E–H (5–8) are diterpenes that feature a 6/8/6 tricyclic ring system. Their structures were unambiguously determined by detailed spectroscopic analyses, X-ray diffractions studies, and ECD calculations. All compounds (1–8) were evaluated for in vitro antimicrobial and cytotoxic activities.
NSTL
Amer Chemical Soc