首页|Neocucurbols A–H, Phomactin Diterpene Derivatives from the Marine-Derived Fungus Neocucurbitaria unguis-hominis FS685

Neocucurbols A–H, Phomactin Diterpene Derivatives from the Marine-Derived Fungus Neocucurbitaria unguis-hominis FS685

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Neocucurbols A–D (1–4) are diterpene derivatives that possess a complex 6/6/5/5/6 polycyclic ring system with a characteristic tetrahedrofuran bridge ring skeleton. Neocucurbols E–H (5–8) are diterpenes that feature a 6/8/6 tricyclic ring system. Their structures were unambiguously determined by detailed spectroscopic analyses, X-ray diffractions studies, and ECD calculations. All compounds (1–8) were evaluated for in vitro antimicrobial and cytotoxic activities.

Hu Jinhua、Zou Zhenxing、Chen Yuchan、Li Saini、Gao Xiaoxia、Liu Zhaoming、Wang Yanlin、Liu Hongxin、Zhang Weimin

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Institute of Microbiology, Guangdong Academy of Sciences

Central South University

Guangdong Pharmaceutical University

Innovation Academy of South China Sea Ecology and Environmental Engineering, Chinese Academy of Sciences

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2022

Journal of natural products

Journal of natural products

CCR
ISSN:0163-3864
年,卷(期):2022.85(8)
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