Tetrahedron letters2022，Vol.995.DOI:10.1016/j.tetlet.2022.153854

Rh(III)-Catalyzed three-component C-H functionalization reaction with vinylene carbonate: Late-stage C-H esterification of indole derivatives

Sun, Meng Li, Bin-Shi Guo, Huai-Xuan Sun, Wei
Tetrahedron letters2022，Vol.995.DOI:10.1016/j.tetlet.2022.153854
✕
  • NSTL
  • Elsevier

Rh(III)-Catalyzed three-component C-H functionalization reaction with vinylene carbonate: Late-stage C-H esterification of indole derivatives

Sun, Meng 1Li, Bin-Shi 1Guo, Huai-Xuan 1Sun, Wei1
扫码查看

作者信息

  • 1. Northwest Univ
  • 折叠

Abstract

An efficient and robust Rh(III)-catalyzed three-component C-H esterification reaction of indole derivatives with vinylene carbonate to access indolyl acetates has been developed.This protocol exhibits high efficiency, good yields, and excellent functional group tolerance. Significantly, this method provides a powerful approach for the late-stage modification of indole-based substrates and natural alcohols.(c) 2022 Elsevier Ltd. All rights reserved.

Key words

Rh(III)-catalyzed/Vinylene carbonate/C-H bond esterification/Indolyl acetate/Late-stage/C2-SELECTIVE CARBENOID FUNCTIONALIZATION/ALKYLATION/(+/-)-CATHARANTHINE/SUBSTITUTION/VINORELBINE

引用本文复制引用

出版年

2022
Tetrahedron letters

Tetrahedron letters

CCR
ISSN：0040-4039
被引量3
参考文献量58
段落导航相关论文