首页|Percutaneous image-guided cryoablation of spinal metastases: A systematic review

Percutaneous image-guided cryoablation of spinal metastases: A systematic review

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  • NSTL
  • Elsevier
? 2021Percutaneous cryoablation (PCA) is a minimally invasive technique that has been recently used to treat spinal metastases with a paucity of data currently available in the literature. A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Prospective or retrospective studies concerning metastatic spinal neoplasms treated with current generation PCA systems and with available data on safety and clinical outcomes were included. In the 8 included studies (7 retrospective, 1 prospective), a total of 148 patients (females = 63%) underwent spinal PCA. Tumors were located in the cervical (3/109 [2.8%], thoracic (74/109 [68.8%], lumbar (37/109 [33.9%], and sacrococcygeal (17/109 [15.6%] regions. Overall, 187 metastatic spinal lesions were treated. Thermo-protective measures (e.g., carbo-/hydro-dissection, thermocouples) were used in 115/187 [61.5%] procedures. For metastatic spinal tumors, the pooled mean difference (MD) in pain scores from baseline on the 0–10 numeric rating scale was 5.03 (95% confidence interval [CI]: 4.24 to 5.82) at a 1-month follow-up and 4.61 (95% CI: 3.27 to 5.95) at the last reported follow-up (range 24–40 weeks in 3/4 studies). Local tumor control rates ranged widely from 60% to 100% at varying follow-ups. Grade I-II complications were reported in 9/148 [6.1%] patients and grade III-V complications were reported in 3/148 [2.0%]) patients. PCA, as a stand-alone or adjunct modality, may be a viable therapy in appropriately selected patients with painful spinal metastases who were traditionally managed with open surgery and/or radiation therapy.

CryoablationSpinal tumorSpine metastases

Sagoo N.S.、Haider A.S.、Ozair A.、Vannabouathong C.、Rahman M.、Haider M.、Sharma N.、Raj K.M.、Raj S.D.、Paul J.C.、Steinmetz M.P.、Adogwa O.、Aoun S.G.、Passias P.G.、Vira S.

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Department of Orthopaedic Surgery University of Texas Southwestern Medical Center

Texas A&M University College of Medicine

King George's Medical University

Department of Neurosurgery Mayo Clinic

John Peter Smith Hospital

Roseman University of Health Sciences South Jordan

Department of Radiology University of Texas Southwestern Medical Center

Department of Radiology Baylor University Medical Center

OrthoConnecticut Orthopedics

Department of Neurological Surgery Cleveland Clinic

Department of Neurological Surgery University of Texas Southwestern Medical Center

Department of Orthopaedic Surgery NYU Langone Orthopedic Hospital

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2022

10.1016/j.jocn.2021.11.008

Journal of clinical neuroscience

Journal of clinical neuroscience

SCI
ISSN：0967-5868
年,卷(期)：2022.96
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