首页|Therapeutic potentials of CRISPR-Cas genome editing technology in human viral infections

Therapeutic potentials of CRISPR-Cas genome editing technology in human viral infections

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Viral infections are a common cause of morbidity worldwide. The emergence of Coronavirus Disease 2019 (COVID-19) has led to more attention to viral infections and finding novel therapeutics. The CRISPR-Cas9 system has been recently proposed as a potential therapeutic tool for the treatment of viral diseases. Here, we review the research progress in the use of CRISPR-Cas technology for treating viral infections, as well as the strategies for improving the delivery of this gene-editing tool in vivo. Key challenges that hinder the widespread clinical application of CRISPR-Cas9 technology are also discussed, and several possible directions for future research are proposed.

CRISPR-CasGene editingInfectionTreatmentVirus

Sajad Najafi、Shing Cheng Tan、Shahin Aghamiri、Pourya Raee、Zahra Ebrahimi、Zahra Kargar Jahromi、Yazdan Rahmati、Javid Sadri Nah、Ahmad Piroozm、Vahid Jajarmij、Hamed Mirzaei

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Student Research Committee, Department of Medical Biotechnology, School of Advanced Technologies in

2022

Biomedicine & pharmacotherapy

Biomedicine & pharmacotherapy

SCI
ISSN:0753-3322
年,卷(期):2022.148