首页|Carboxylated nanocellulose dispersed nitrogen doped graphene nanosheets and sodium dodecyl sulfate modified electrochemical sensor for the simultaneous determination of paracetamol and naproxen sodium

Carboxylated nanocellulose dispersed nitrogen doped graphene nanosheets and sodium dodecyl sulfate modified electrochemical sensor for the simultaneous determination of paracetamol and naproxen sodium

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An innovative electrochemical sensing platform was fabricated for the simultaneous determination of paracetamol (PCT) and naproxen sodium (NPX). The glassy carbon electrode (GCE) was modified with a hybrid porous nanocomposite of carboxylated nanocellulose (CNCS), nitrogen doped graphene (NDG) and an anionic surfactant sodium dodecyl sulfate (SDS) by simple ultrasonication and drop-casting method. The (CNCS-NDG)-SDS nanocomposite showed high electrocatalytic performance towards the redox reaction of PCT and the oxidation of NPX between 0.2 V and 0.9 V at 0.1 V s- 1 with broad linear ranges from 0.01 to 90 mu M and 0.1 to 60 mu M for PCT and NPX, respectively. The limit of detection is 0.0015 mu M and 0.0018 mu M for PCT and NPX, respectively, while the limit of quantification is 0.015 mu M and 0.018 mu M, respectively. The (CNCS-NDG)-SDS/GCE sensor showed good stability, reproducibility and repeatability for the electrochemical determination of PCT and NPX.

Electrochemical sensorTEMPOCarboxylated-nanocelluloseNitrogen doped grapheneSodium dodecyl sulfateDICLOFENAC SODIUMCARBON NANOTUBESASCORBIC-ACIDGC-MSACETAMINOPHENELECTRODENANOCOMPOSITEPLATINUMNANOPARTICLESMWCNTS

Shalauddin, Md、Akhter, Shamima、Basirun, Wan Jefrey、Anuar, Nadzirah Sofia、Akbarzadeh, Omid、Mohammed, Mohammed Alhaji、Johan, Mohammad Rafie

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Univ Malaya

2022

Measurement

Measurement

SCI
ISSN:0263-2241
年,卷(期):2022.194
  • 10
  • 54