L-proline on multi-wall carbon nanotubes (L-proline/MWCNTs) catalysts doped with suitable auxiliary support materials are successfully applied in the continuous flow catalytic syntheses, including Aldol reaction, Mannich reaction and Knoevenagel condensation reaction. With the advantages of easy operation, high efficiency and excellent stability, this method is promising in large-scale synthesis. (c) 2022 Elsevier Ltd. All rights reserved.
Key words
L -proline/MWCNTs/Auxiliary support materials/Continuous flow synthesis/Column reactor/Catalysis