Synthesis of optically pure, deuterated Maruoka Catalysts and their chemical reactivity
Li, Zhurong 1Liu, Yan 1Murayama, Sei 2Naka, Hiroshi 2Maruoka, Keiji 1Liang, Huatai1
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作者信息
1. Guangdong Univ Technol
2. Kyoto Univ
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Abstract
A synthetic route to optically pure, deuterated D-4-Simplified Maruoka Catalyst has been developed from commercially available optically pure binaphthol. Additionally, optically pure, deuterated D-2-Simplified Maruoka Catalyst has been prepared in one step from commercially available optically pure Simplified Maruoka Catalyst (R). The chemical reactivity of deuterated D-4- and D-2-Simplified Maruoka Catalysts has been investigated in comparison to that of the original Simplified Maruoka Catalyst (R) by carrying out deprotonation experiments on the acidic benzylic hydrogens of the catalysts under basic conditions that induce the Stevens rearrangement. (C) 2022 Elsevier Ltd. All rights reserved.
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Elsevier