首页|Five new germacrane sesquiterpenes with anti-inflammatory activity from Salvia petrophila

Five new germacrane sesquiterpenes with anti-inflammatory activity from Salvia petrophila

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  • NSTL
  • Elsevier
? 2021 Phytochemical Society of EuropeFive new germacrane sesquiterpene lactones, petrophins A–E (1–5), were isolated from the whole herbs of Salvia petrophila. The structures were established using spectroscopic analysis (1D and 2D NMR, HR-ESI-MS) and compatible with values in the literature. These sesquiterpenes are unusual with an endocyclic double bond in the γ-lactone ring. All the isolated compounds were evaluated for their inhibitory effects on the LPS-induced nitric oxide production using murine macro-phage RAW264.7 cells.

Anti-inflammatory activityGermacrane sesquiterpenesNitric oxide (NO)Petrophins A–ESalvia petrophila

Zou Z.-Q.、Ning D.-S.、Liu Y.、Fu Y.-X.、Li L.-C.、Pan Z.-H.

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Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization Guangxi Institute of Botany Chinese Academy of Sciences

2022

10.1016/j.phytol.2021.12.001

Phytochemistry Letters

Phytochemistry Letters

SCI
ISSN：1874-3900
年,卷(期)：2022.47
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