Tetrahedron letters2022，Vol.953.DOI:10.1016/j.tetlet.2022.153751

Phaseollin A, a novel pterocarpan with a unique 6/7/5/6/6 skeleton from Phaseolus lunatus L

Wu, Heng Bian, Jin-hui Li, Kun Wang, Ya-lan Tan, Yu-zhu Yan, Hong-ling Chen, Na Li, Hong-xiang Yu, Han Li, Wan Lu, Guang-hua
Tetrahedron letters2022，Vol.953.DOI:10.1016/j.tetlet.2022.153751
✕
  • NSTL
  • Elsevier

Phaseollin A, a novel pterocarpan with a unique 6/7/5/6/6 skeleton from Phaseolus lunatus L

Wu, Heng 1Bian, Jin-hui 1Li, Kun 1Wang, Ya-lan 1Tan, Yu-zhu 1Yan, Hong-ling 1Chen, Na 2Li, Hong-xiang 1Yu, Han 1Li, Wan 1Lu, Guang-hua1
扫码查看

作者信息

  • 1. Chengdu Univ Tradit Chinese Med
  • 2. Chengdu Jiuzhentang Hlth Management Ltd Liabil Co
  • 折叠

Abstract

A novel pterocarpan, named phaseollin A (1) was isolated from Lima bean (the seeds of Phaseolus lunatus L.). The structure of 1 was elucidated by the extensive spectroscopic analysis (1D and 2D NMR, HR-ESIMS) as well as the experimental and calculated ECD data analysis. Compound 1 showed moderate activity of inhibiting NO production on lipopolysaccharide (LPS)-induced RAW264.7 cells with IC50 value of 37.13 & nbsp;+/- 2.58 lM.(C 2022 Elsevier Ltd. All rights reserved.

Key words

Phaseollin A/Pterocarpans/Phaseolus lunatus/Anti-inflammation

引用本文复制引用

出版年

2022
Tetrahedron letters

Tetrahedron letters

CCR
ISSN：0040-4039
参考文献量18
段落导航相关论文