首页|Prostatic Artery Embolization for Treatment of Lower Urinary Tract Symptoms: A Markov Model-Based Cost-Effectiveness Analysis
Prostatic Artery Embolization for Treatment of Lower Urinary Tract Symptoms: A Markov Model-Based Cost-Effectiveness Analysis
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
NSTL
Elsevier
Purpose: The aim of this study was to investigate whether prostatic artery embolization (PAE) can be considered a long-term cost-effective treatment option in patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia in comparison to transurethral resection of the prostate (TURP). Methods: The in-hospital costs of PAE and TURP in the United States were obtained from a recent cost analysis. Clinical outcomes including nature and rate of adverse events for TURP and PAE along with rates of retreatment because of complications or clinical failure were obtained from peer-reviewed literature. A decision tree-based Markov model was created, analyzing long-term cost-effectiveness for TURP and PAE from a US health care sector perspective. Cost-effectiveness over a time frame of 5 years was estimated while assuming a willingness to pay of $50,000 per quality-adjusted life-year (QALY). The primary outcome was incremental cost-effectiveness ratio. Results: PAE resulted in overall cost of $6,464.92 and an expected outcome of 4.566 QALYs. In comparison, TURP cost $9,221.09 and resulted in expected outcome of 4.577 QALYs per treatment. The incremental cost-effectiveness ratio for TURP was $247,732.65 per QALY. On the basis of the willingness-to-pay threshold, PAE is cost effective compared with TURP. Conclusions: On the basis of our model, PAE in comparison with TURP can be regarded as a cost-effective treatment option for patients with lower urinary tract symptoms within the US health care system.
Prostatic artery embolizationtransurethral resection of the prostatecost-effectivenessbenign prostate hyperplasialower urinary tract symptomsTRANSURETHRAL RESECTIONNATURAL-HISTORYHYPERPLASIAMENFINASTERIDERETENTIONTHERAPYHEALTHTURPPAE
Rink, Johann S.、Froelich, Matthias F.、McWilliams, Justin P.、Gratzke, Christian、Huber, Thomas、Gresser, Eva、Schoenberg, Stefan O.、Diehl, Steffen J.、Noerenberg, Dominik
展开 >
Dept Radiol & Nucl Med,Mannheim Univ
Dept Radiol,Ronald Reagan UCLA
Fac Med,Univ Freiburg
TUM Sch Med,Klinikum Rechts Isar Tech Univ Munchen
NSTL
Elsevier
