首页|Acremolides A-D, lipodepsipeptides from an Australian marine-derived fungus, Acremonium sp.
Acremolides A-D, lipodepsipeptides from an Australian marine-derived fungus, Acremonium sp.
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NSTL
An Australian estuarine isolate of an Acremonium sp. (MST-MF588a) yielded the two known compounds 19- O-acetylchaetoglobosin D ( 1) and 19- O-acetylchaetoglobosin B ( 2), as the sole cytotoxic principles, along with the known aromatic metabolite RKB 3564S ( 3), and a novel family of lipodepsipeptides, acremolides A-D ( 4- 7). Structures were assigned to 4- 7 on the basis of detailed spectroscopic analysis and chemical derivatization and by application of a new C 3 Marfey's method for amino acid analysis.
NSTL
