首页|A molecularly imprinted biosensor based on water-compatible and electroactive polymeric nanoparticles for lysozyme detection
A molecularly imprinted biosensor based on water-compatible and electroactive polymeric nanoparticles for lysozyme detection
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NSTL
Elsevier
A molecularly imprinted biosensor for lysozyme based on the polymer nanoparticles self-assembled from watersoluble and electroactive poly (gamma-glutamic acid) modified with 3-aminothiophene copolymer were prepared. The water-soluble copolymer made imprinting of lysozyme in aqueous solution possible and thus facilitated improvement of the activity of LYS. Subsequent electro-polymerization not only locked the recognition site between copolymer and lysozyme but also created a conductive polymer network, which can enhance the electron transfer rate and increase the conductivity of the film. The prepared molecularly imprinted biosensor exhibited a wide linear range from 1 x 10-10 to 1 x 10-5 mg mL-1, and satisfactory selectivity, stability, repeatability for lysozyme detection.
NSTL
Elsevier
