首页|Low protective PON1 lactonase activity in an Arab population with high rates of coronary heart disease and diabetes
Low protective PON1 lactonase activity in an Arab population with high rates of coronary heart disease and diabetes
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NSTL
Elsevier
Background: Recent studies showing that high density lipoproteins (HDL) can effect plaque regression indicate that recent trial failures do not exclude an atheroprotective role of HDL Instead, they highlight differences between HDL function and measured HDL-cholesterol (HDL-C). PON1 is one key functional activity of HDL. Urban Palestinians have lower HDL-C and a higher incidence and mortality of coronary heart disease than those of Israelis. We hypothesized that the cardioprotective PON1 lactonase and arylesterase activities and PON1 functional genotype may differ between Palestinians and Israelis.
NSTL
Elsevier
