首页|IL-10 is associated with increased mu-opioid receptor levels in major depressive disorder
IL-10 is associated with increased mu-opioid receptor levels in major depressive disorder
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NSTL
Elsevier
Objective: Activation of the immune-inflammatory response system (IRS) and the compensatory immune-regulatory system (CIRS) and aberrations in endogenous opioids play a role in the pathophysiology of major depressive disorder (MDD). There are no studies which examined the associations between both systems in MDD. The aim of the present study was to examine the relation between beta-Endorphin (beta-EP), Endomorphin-2, and their mu-opioid receptor (MOR) as well as interleukin (IL)-6 and IL-10, an anti-inflammatory cytokine, in MDD patients.