首页|Isolation, Characterization and Antibacterial Studies of Three New Chemical Constituents Isolated from Viburnum grandiflorum
Isolation, Characterization and Antibacterial Studies of Three New Chemical Constituents Isolated from Viburnum grandiflorum
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NSTL
Springer Nature
Three new compounds "Viburnoate A-C" and two known compounds, namely, 4, 4-dimethyl-hexan-3-ol (1) and 4-tert-butyl-benzoic acid isobutyl ester (2), were isolated from ethyl acetate (EtOAc) fraction of medicinally important plant Viburnum grandiflorum. These compounds were isolated from the plant material by chromatographic techniques and then characterized using mass spectrometry, FTIR, H-1 NMR and C-13 NMR spectroscopic techniques. The study indicated Viburnoate A-C as new compounds. Viburnoate A, Viburnoate C, and isobutyl 4-(tert-butyl) benzoate are aromatic esters, while Viburnoate B and 4, 4-dimethylhexanol are aromatic aldehyde and alcohol, respectively. The isolated compounds were tested against bacteria (E. coli and S. aureus). The inhibition zones of Viburnoate A-C compounds against E. coli were 9 (+/- 0.2), 11 (+/- 0.4), 9 (+/- 0.4) mm and those against S. aureus were 13 (+/- 0.3), 16 (+/- 0.2), 15 (+/- 0.3) mm, respectively. The results indicated that Viburnoate B exhibited highest inhibition activity against both bacteria, which might be due to less crowded oxygen species.
NSTL
Springer Nature
