首页|Iridoid glucosides from the leaves of Vitex negundo var. cannabifolia

Iridoid glucosides from the leaves of Vitex negundo var. cannabifolia

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  • NSTL
  • Elsevier
? 2021 Phytochemical Society of EuropeFive new iridoid glucosides, cannabifolisides A–E (1 – 5), together with nine analogues (6 – 14), were isolated from the leaves of Vitex negundo var. cannabifolia. Their structures were elucidated by spectroscopic data (NMR, UV, IR, and MS) analyses and comparison of their spectroscopic and physical data with the literature values. The protective effect of isolated compounds on human gastric epithelial cells were evaluated by measuring the enhanced cell viability of GES-1 cell insulted by TCA. Among these, compounds 4, 6, 8, 10, 12, and 14 remarkably increased the cell viability in a concentration-depend manner.

Human gastric epithelial cellsIridoid glucosideStomachacheVerbenaceaeVitex negundo var. cannabifolia

Sun J.、Ma J.、Li M.、Wang R.、Liang N.、Zhao Y.、Zheng J.、Song Y.、Tu P.、Huo H.、Li J.

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Modern Research Center for Traditional Chinese Medicine School of Chinese Materia Medica Beijing University of Chinese Medicine

2022

10.1016/j.phytol.2021.11.008

Phytochemistry Letters

Phytochemistry Letters

SCI
ISSN：1874-3900
年,卷(期)：2022.47
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