首页|POLAR METABOLITES FROM THE ACTINOBACTERIUM Isoptericola chiayiensis ISOLATED FROM MANGROVE SOIL
POLAR METABOLITES FROM THE ACTINOBACTERIUM Isoptericola chiayiensis ISOLATED FROM MANGROVE SOIL
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Actinobacteria are microscopic soil microbes and are well known for their ability to produce a wide variety of secondary metabolites with antimicrobial,insecticidal,and many other bioactivities,which are becoming important resources of new pharmaceuticals and lead compounds(1-3),They are gram positive,free-living saprophytic bacteria that are found widely distributed in soil,water,and colonizing plants.Actinobacteria inhabitants have been identified as one of the major groups of soil population(2,3),which may vary with the soil type.The genus most frequently found in this order is the genus Streptomyces,whose many secondary metabolites have often been explored.The actinobacteria are noteworthy as antibiotic producers and the Streptomyces sp.are especially prolific and can produce a great many antibiotics and a variety of bioactive secondary metabolites.In the course of our search for biologically active substances from mangrove soil-derived actinobacteria,we isolated a strain named 06182M-1~T from a soil sample of Chiayi County,Taiwan with a unique morphology(4).This strain was determined to be e Isoptericola chiayiensis(Promicromonosporaceae)based on their phenotypic and genotypic data(4).The Promicromonosporaceae(Actinomycetales,Actinobacteria)constitutes a large family of bacteria.In order to find new bioactive molecules,rare genera in this group have been identified and studied,including the genus Isoptericola.Isoptericola,a genus of bacteria that was only discovered in 2004; currently there are only eight species.It is an actinobacteria that resembles bacteria in morphology.There are no aerial hyphae.The vegetative hyphae will break into short rods or globules that are not motile.Some species are anaerobic or facultative anaerobic.Mainly isolated from high-salinity soil,termite intesthes,limestone or general soil,and other environments,there are few studies on its metabolites.This strain is a new strain isolated from the mangrove wetland in Chiayi County.
Nanthaphong Khamthong、Ming-Jen Cheng、Ming-Der Wu
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College of Oriental Medicine,Rangsit University,Pathum Thani 12000,Thailand
Bioresource Collection and Research Center(BCRC),Food Industry Research and Development Institute(FIRDI),Hsinchu 300,Taiwan
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