首页|ISOLATION AND CHARACTERIZATION OF HEPATOPROTECTIVE ANTHRAQUINONE DERIVATIVES FROM Cucumis bisexualis
ISOLATION AND CHARACTERIZATION OF HEPATOPROTECTIVE ANTHRAQUINONE DERIVATIVES FROM Cucumis bisexualis
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A new anthraquinone,named 1,3-dihydroxyl 2-methylene-(1'-isopentyloxy)-6-methoxymethyl-8-(6",7",8"-trihydroxyphenylketonyl)-9,10-anthraquinone(1),and nine known anthraquinone derivatives(2-10),were isolated from Cucumis bisexualis for the first time.Compounds 1-10 were evaluated for their hepatoprotective activity in human L-02 cells compared with the positive control bifendatatum.Among them,compounds 1,3,and 8 exhibited moderate hepatoprotective activity in the proliferation of L-02 cells.
Key Laboratory of Modern Preparation of TCM of Ministry of Education & Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic Medicine,Jiangxi University of Traditional Chinese Medicine,330004,Nanchang,Jiangxi,P.R.China