首页|DETECTION OF CEREBRAL HIGH-INTENSITY TRANSIENT SIGNALS BY NEODOPPLER DURING CARDIAC CATHETERIZATION AND CARDIAC SURGERY IN INFANTS

DETECTION OF CEREBRAL HIGH-INTENSITY TRANSIENT SIGNALS BY NEODOPPLER DURING CARDIAC CATHETERIZATION AND CARDIAC SURGERY IN INFANTS

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  • NSTL
  • Elsevier
There is a risk of gaseous and solid micro-embolus formation during transcatheter cardiac interventions and surgery in children with congenital heart disease (CHD). Our aim was to study the burden of high intensity transient signals (HITS) during these procedures in infants. We used a novel color M-mode Doppler (CMD) technique by NeoDoppler, a non-invasive ultrasound system based on plane wave transmissions for transfontanellar continuous monitoring of cerebral blood flow in infants. The system displays CMD with 24 sample volumes and a Doppler spectrogram. Infants with CHD undergoing transcatheter interventions (n = 15) and surgery (n = 13) were included. HITS were manually detected based on an "embolic signature " in the CMD with corresponding intensity increase in the Doppler spectrogram. Embolus-to-blood ratio (EBR) defined HITS size. A total of 1169 HITS with a median EBR of 9.74 dB (interquartile range [IQR]: 5.10-15.80 dB) were detected. The median number of HITS in the surgery group was 45 (IQR: 11-150), while in the transcatheter group the median number was 12 (IQR: 7-24). During cardiac surgery, the highest number of HITS per hour was seen from initiation of cardiopulmonary bypass to aortic X-clamp. In this study we detected frequent HITS and determined the feasibility of using NeoDoppler monitoring for HITS detection. (C) 2022 The Author(s). Published by Elsevier Inc. on behalf of World Federation for Ultrasound in Medicine & Biology. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

High-intensity transient signalsMicro-embolic signalsBrain embolismsDoppler ultrasound monitoringColor M-mode DopplerCongenital heart diseasePOWER M-MODETRANSCRANIAL DOPPLERNEURODEVELOPMENTAL OUTCOMESCARDIOPULMONARY BYPASSTRANSCATHETER CLOSUREMICROEMBOLI DETECTIONBLOOD-FLOWULTRASOUNDEMBOLIDIFFERENTIATION

Leth-olsen, Martin、Dohlen, Gaute、Torp, Hans、Nyrnes, Siri Ann

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Fac Med & Hlth Sci,Norwegian Univ Sci & Technol

Dept Pediat Cardiol,Oslo Univ Hosp

2022

10.1016/j.ultrasmedbio.2022.02.021

Ultrasound in Medicine and Biology

Ultrasound in Medicine and Biology

EISCI
ISSN：0301-5629
年,卷(期)：2022.48(7)
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