首页|Modeling the Effects of Vaccination and Treatment on Tuberculosis Transmission Dynamics

Modeling the Effects of Vaccination and Treatment on Tuberculosis Transmission Dynamics

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In this study, we develop and analyze a deterministic mathematical model for tuberculosis (TB) transmission dynamics. ?e model includes vaccination for newborns and treatment for both high-risk latent and active TB patients. ?e stability of disease-free equilibrium point is discussed in detail. In the numerical simulation, the model parameters are estimated using reported TB incidence data in Ethiopia from the years 2003 to 2017, and R_0 is calculated as R_0≈2.13. Finally, the sensitivity indices of R_0 with respect to the model parameters are performed, and their corresponding graphical results are presented. Our results quantify the positive in?uence of vaccination and the treatment for high-risk latent and active TB patients on the control of tuberculosis.

ModelingEffects of VaccinationTuberculosis Transmission Dynamics

Ashenafi Kelemu Mengistu、Peter J. Witbooi

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Department of Mathematics and Applied Mathematics, University of the Western Cape, Private Bag X17, Bellville 7535, South Africa

2019

Journal of applied mathematics

Journal of applied mathematics

EI
ISSN:1110-757X
年,卷(期):2019.2019(Pt.4)
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