首页|50 years of chiral liquid Chromatography. How it started
50 years of chiral liquid Chromatography. How it started
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NSTL
Elsevier
The birth of modern chiral liquid chromatography can be traced back to the years 1968-71 when the first complete resolution of a racemic amino acid was obtained and presented in the literature. Extreme enantioselectivity was achieved due to the introduction of ligand exchange principle, i.e. participation of a copper ion in the solute-sorbent interactions. Simultaneously, first microporous (hypercrosslinked) polymeric matrixes were introduced, thus enhancing the chromatographic efficiency of the process. (c) 2022 Elsevier B.V. All rights reserved.
NSTL
Elsevier
