首页|Two new C21 steroids from Lepidogrammitis drymoglossoides (Bak.) Ching

Two new C21 steroids from Lepidogrammitis drymoglossoides (Bak.) Ching

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? 2022 Phytochemical Society of EuropeTwo new compounds lepidodromos A-B and (1-2) have been isolated from the methanol-soluble extract of the aerial parts of Lepidogrammitis drymoglossoides (Bak.) Ching (Family: Polypodiaceae) and their structures were determined by 1D, 2D NMR, and HR-ESI–MS. The comparisons of experimental and calculated CD curves were used to determine their absolute configurations. The antiproliferative test indicated that both compounds 1-2 displayed moderate biological activity against Hela cells with IC50 values of 17.8 and 20.4 μM, respectively.

C21 SteroidsLepidogrammitis drymoglossoidesPolypodiaceae

Guo H.-W.、Huang J.、Tian Y.-G.、Liu Y.-H.、Wei H.、Wang J.-X.

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College of Biology and Environmental Science Jishou University

School of Pharmaceutical Sciences Jishou University

School of Medicine Jishou University

2022

Phytochemistry Letters

Phytochemistry Letters

SCI
ISSN:1874-3900
年,卷(期):2022.49
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