首页|Acetaminophen and Xenobiotic Metabolites in Human Milk and the Development of Bronchopulmonary Dysplasia and Retinopathy of Prematurity in a Cohort of Extremely Preterm Infants

Acetaminophen and Xenobiotic Metabolites in Human Milk and the Development of Bronchopulmonary Dysplasia and Retinopathy of Prematurity in a Cohort of Extremely Preterm Infants

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  • NSTL
  • Elsevier
? 2022 Elsevier Inc.This retrospective cohort study sought to identify the association between certain xenobiotic metabolites in maternal breast milk and the diagnoses of bronchopulmonary dysplasia and retinopathy of prematurity in extremely preterm infants. Several acetaminophen metabolites were associated with a 3- to 6-fold increased odds of these disorders, and metabolites of certain food products, benzoate, and caffeine were associated with decreased odds.

acetaminophenbreast milkbronchopulmonsary dysplasiapreterm infantxenobiotics

Santoro K.L.、Yakah W.、Singh P.、Ramiro-Cortijo D.、Medina-Morales E.、Freedman S.D.、Martin C.R.

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Division of Newborn Medicine Boston Children's Hospital Harvard Medical School

Department of Neonatology Beth Israel Deaconess Medical Center Harvard Medical School

Division of Gastroenterology Beth Israel Deaconess Medical Center Harvard Medical School

2022

10.1016/j.jpeds.2022.01.030

The Journal of pediatrics

The Journal of pediatrics

ISSN：0022-3476
年,卷(期)：2022.244
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