首页|Impairment in selenocysteine synthesis as a candidate mechanism of inducible coagulopathy in COVID-19 patients
Impairment in selenocysteine synthesis as a candidate mechanism of inducible coagulopathy in COVID-19 patients
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
NSTL
Elsevier
Coagulopathy has recently been recognized as a recurring complication of COVID-19， most typically associated with critical illness。 There are epidemiological， mechanistic and transcriptomic evidence that link Selenium with SARS-CoV-2's intracellular latency。 Taking into consideration the vital role of selenoproteins in maintaining an adequate immune response， endothelial homeostasis and a non-prothrombotic platelet activation status， we propose that impairment in selenocysteine synthesis， via perturbations in the aforementioned physiological functions， potentially constitutes a mechanism of coagulopathy in COVID 19 patients other than those developed in critical illness。
NSTL
Elsevier
