1. Sun Yat Sen Univ, Dept Hepatobiliary Surg, Affiliated Hosp 3, Guangzhou 510630, Guangdong, Peoples
2. Sun Yat Sen Univ, Dept Gynecol & Obstet, Sun Yat Sen Mem Hosp, Yanjiang Rd 107, Guangzhou 510060
折叠
Abstract
Aim Abnormal natural killer (NK) cell activity has been suggested to be a high-risk factor associated with unexplained recurrent spontaneous abortion (URSA). Intralipid, like immunoglobulin, is able to lower the activity of NK cells, which has been reported to be useful for improving URSA outcomes in pregnancy. This study aimed to determine whether intralipid could be used as an alternative treatment to intravenous immunoglobulin (IVIG) which is expensive and has many side-effects.
Key words
NK cells/Unexplained recurrent spontaneous abortion/Intralipid/Cell invasion