Visible light-induced radical cascade reaction of acryloylbenzamides with N-hydroxyphthalimide esters

Cai, Xingxing Liu, Yihuo Ding, Siyu Fu, Jiahui Li, Jinghua Cheng, Dongping Xu, Xiaoliang

Tetrahedron letters2022，Vol.954.DOI:10.1016/j.tetlet.2022.153722

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NSTL
Elsevier

Visible light-induced radical cascade reaction of acryloylbenzamides with N-hydroxyphthalimide esters

Cai, Xingxing ¹Liu, Yihuo ¹Ding, Siyu ¹Fu, Jiahui ¹Li, Jinghua ¹Cheng, Dongping ¹Xu, Xiaoliang¹

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作者信息

1. Zhejiang Univ Technol
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Abstract

An efficient and mild cascade reaction of acryloylbenzamides with N-hydroxyphthalimide (NHPI) esters is disclosed. It goes through radical addition and subsequent cyclization to give 4-alkylated isoquinolinediones in the presence of visible light and photocatalyst Ir[dF(CF3)ppy(2)](dtbbpy)PF6.(C) 2022 Elsevier Ltd. All rights reserved.

Key words

Isoquinolinediones/Acryloylbenzamides/Cyclization reaction/Visible light/Photocatalysis/SELECTIVE INHIBITORS/METHACRYLOYL BENZAMIDES/PHOTOREDOX CATALYSIS/ACTIVATED ALKENES/RNASE-H/ADDITION/CYCLIZATION/ALKYLARYLATION/CYCLIZATION/ALKYLATION/DESIGN

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出版年

2022

Tetrahedron letters

CCR

ISSN：0040-4039

被引量5

参考文献量47

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