首页|Piperhancosides A?C, new lignan glycosides from the stems of Piper hancei Maxim

Piperhancosides A?C, new lignan glycosides from the stems of Piper hancei Maxim

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  • NSTL
  • Elsevier
? 2022 Phytochemical Society of EuropeThree new lignan glycosides, piperhancosides A?C (1?3), and two known compounds (4?5) were isolated from the n-BuOH extract of the stems of Piper hancei Maxim. The planar structures of the new compounds were elucidated by extensive spectroscopic analyses. Their relative and absolute configurations were determined by coupling constants, chemical shift differences, acid hydrolysis, enzymatic hydrolysis, and experimental ECD spectra. All the isolates were evaluated for their antineuroinflammatory and antioxidant activities, and compounds 4 and 5 showed significant DPPH.+ radical scavenging ability with EC50 value of 14.07 and 16.48 μM, respectively.

Absolute configurationsDPPH.+ radical scavenging activityLignan glycosidesPiper hancei Maxim.Piperaceae

He S.、Chen M.-L.、Yang F.、Liang D.

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State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources Collaborative Innovation Center for Guangxi Ethnic Medicine School of Chemistry and Pharmaceutical Sciences Guangxi Normal University

2022

10.1016/j.phytol.2022.05.009

Phytochemistry Letters

Phytochemistry Letters

SCI
ISSN：1874-3900
年,卷(期)：2022.50
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