首页|The danger of dichloromethane in the synthesis and application of imidazole-based dyes
The danger of dichloromethane in the synthesis and application of imidazole-based dyes
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
NSTL
In this paper,a lophine-based phenol compound has been prepared and identified as an efficient chromophore for the determination of hydrogen peroxide(H2O2)with enzymatic method.A dry chemistry analytic agent was also prepared involving this compound,showing good accuracy in the determination of uric acid.However,a commonly used solvent dichloromethane(DCM)could react with this imidazole derivative when the reaction mixture was irradiated under UV(365 nm).We explored the possible mechanism and identified several byproducts caused by the acidity and ultraviolet oxidation of DCM.Caution should be taken in the synthesis and application of such imidazole-based dyes in DCM,especially when phenol group was introduced to the imidazole moiety.
ImidazoleUltraviolet oxidation of DCMHydrogen peroxide detection
Zhizhou Liu、Chao Li、Chen Chen
展开 >
CAS Key Lab of Bio-Medical Diagnostics,Suzhou Institute of Biomedical Engineering and Technology,Chinese Academy of Sciences,Suzhou,Jiangsu,215163,People's Republic of China
NSTL
