首页|The Role of Chronic Conditions in Outcomes following Noncardiac Surgery in Children with Congenital Heart Disease

The Role of Chronic Conditions in Outcomes following Noncardiac Surgery in Children with Congenital Heart Disease

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? 2022 Elsevier Inc.Objectives: To compare outcomes in children with congenital heart disease (CHD) undergoing noncardiac surgery by presence of chronic conditions and identify associated risk factors. Study design: Retrospective analysis of 14 031 children with CHD who underwent noncardiac surgery in the 2016 Healthcare Cost and Utilization Project Kid's Inpatient Database. Multivariable regression was used to assess patient and hospital factors associated with in-hospital mortality and length of stay (LOS). Results: Overall, 94% had at least 1 chronic condition. The in-hospital mortality rate was 5.6%. Neonates with CHD only had the highest mortality (15.6%); otherwise, children with CHD and at least 1 chronic condition had higher mortality than patients with CHD only (infant 3.93%, child 1.22%, adolescent 1.04% vs 2.34%, 0%, and 0%). Neonates (OR, 15.5; 95% CI, 7.1-34.1 vs adolescent), number of chronic conditions (OR, 1.34; 95% CI, 1.27-1.42), chronic conditions type (circulatory system; OR 2.46; 95% CI, 2.04-2.98), and low socioeconomic status (OR, 1.36; 95% CI, 1.05-1.77) were associated with increased mortality. The median LOS was 20 days (IQR, 5-66). Those with CHD and at least 1 chronic condition had a greater LOS (21 days; IQR, 5-68) than those with CHD only (9 days; IQR, 3-46). Neonates (adjusted coefficient, 44.3; 95% CI, 40.3-48.3 vs adolescent), Black race (adjusted coefficient, 4.78; 95% CI, 2.27-7.3), chronic condition indicator number (adjusted coefficient, 5.17; 95% CI, 4.56-5.78), and subtype (adjusted coefficient, 23.6; 95% CI, 20.4-26.7) were associated with a prolonged LOS. Conclusions: Most children with CHD who undergo noncardiac surgery have at least 1 chronic condition. Age, chronic conditions type and number, low socioeconomic status, and Black race impart increased risks of in-hospital mortality and prolonged LOS. Further research is needed to evaluate the impact of specific chronic conditions and determine barriers to equitable care.

Valencia E.、Staffa S.J.、Faraoni D.、Berry J.G.、DiNardo J.A.、Nasr V.G.

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Department of Cardiology Boston Children's Hospital Harvard Medical School

Department of Anesthesiology Critical Care and Pain Medicine Boston Children's Hospital Harvard

Department of Anesthesiology Perioperative and Pain Medicine Texas Children's Hospital Baylor

Complex Care Division of General Pediatrics Boston Children's Hospital Harvard Medical School

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2022

The Journal of pediatrics

The Journal of pediatrics

ISSN:0022-3476
年,卷(期):2022.244
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