首页|Insight into the pharmacological effects of andrographolide in musculoskeletal disorders

Insight into the pharmacological effects of andrographolide in musculoskeletal disorders

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Andrographis paniculata (A. paniculata) is a traditional herbal medicine that has been widely used in Asian countries for hundreds of years. Andrographolide (AG) is a diterpene lactone extracted from A. paniculata. Owing to the in-depth study of pharmacological mechanisms, the therapeutic potential of AG, including its anti-inflammatory, anti-tumor, and immunoregulatory attributes, has attracted the attention of many researchers. Studies testing the therapeutic effects of AG have demonstrated desirable results in the treatment of a variety of clinical diseases. With high safety and various biological functions, AG might be a promising candidate for the treatment of musculoskeletal disorders. Here, we review all available literatures to summarize the pharmacological effects of AG and facilitate further researches on musculoskeletal diseases.

AndrographolideMusculoskeletal disordersInflammationSignaling pathways

Ming-Yang Liu、Hai-jun Li、Chen Yang、Wei-dong Zang、Zhen-dong Liu、Liang Zhang、Pan-hui Li、Yong-jie Zhu、Yao-ye Zhao、Run-ze Liu、Yan-zheng Gao

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Department of Orthopedics, People's Hospital ofZhengzhou University, Henan Provincial People's

2022

Biomedicine & pharmacotherapy

Biomedicine & pharmacotherapy

SCI
ISSN:0753-3322
年,卷(期):2022.146