首页|Contributions of the Women's Health Initiative to Cardiovascular Research: JACC State-of-the-Art Review

Contributions of the Women's Health Initiative to Cardiovascular Research: JACC State-of-the-Art Review

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  • NSTL
  • Elsevier
? 2022 American College of Cardiology FoundationThe WHI (Women's Health Initiative) enrolled 161，808 racially and ethnically diverse postmenopausal women， ages 50-79 years， from 1993 to 1998 at 40 clinical centers across the United States。 In its clinical trial component， WHI evaluated 3 randomized interventions (menopausal hormone therapy; diet modification; and calcium/vitamin D supplementation) for the primary prevention of major chronic diseases， including cardiovascular disease， in older women。 In the WHI observational study， numerous clinical， behavioral， and social factors have been evaluated as predictors of incident chronic disease and mortality。 Although the original interventions have been completed， the WHI data and biomarker resources continue to be leveraged and expanded through ancillary studies to yield novel insights regarding cardiovascular disease prevention and healthy aging in women。

cardiovascular diseaseepidemiologymenopausepreventionrandomized trialwomen's health

LaMonte M.J.、Manson J.E.、Anderson G.L.、Baker L.D.、Bea J.W.、Eaton C.B.、Follis S.、Hayden K.M.、Kooperberg C.、LaCroix A.Z.、Limacher M.C.、Neuhouser M.L.、Odegaard A.、Perez M.V.、Prentice R.L.、Reiner A.P.、Stefanick M.L.、Van Horn L.、Wells G.L.、Whitsel E.A.、Rossouw J.E.

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Department of Epidemiology and Environmental Health University at Buffalo–SUNY

Department of Medicine Brigham and Women's Hospital Harvard Medical School

Division of Public Health Sciences Fred Hutchinson Cancer Research Center

Department of Gerontology and Geriatric Medicine Wake Forest University School of Medicine

Department of Health Promotion Science University of Arizona

Department of Family Medicine and Epidemiology Brown University

Stanford Prevention Research Center Department of Medicine Stanford University

Department of Social Sciences and Health Policy Wake Forest University School of Medicine

Division of Epidemiology Herbert Wertheim School of Public Health and Human Longevity Science

Department of Internal Medicine University of Florida

Department of Epidemiology University of California

Department of Medicine Stanford University

Department of Epidemiology University of Washington

Department of Preventive Medicine Northwestern University

Department of Medicine University of Alabama

Department of Epidemiology Gillings School of Global Public Health University of North Carolina

National Heart Lung and Blood Institute National Institutes of Health

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2022

10.1016/j.jacc.2022.05.016

Journal of the American College of Cardiology

Journal of the American College of Cardiology

ISTP
ISSN：0735-1097
年,卷(期)：2022.80(3)
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