In this next volume in the Cell Biology and Translational Medicine series, we continue to explore fundamentals of stem cell biology as well as their potential utility in regenerative medicine applications. Amongst topics explored in this volume are recent advances in understanding of the epithelial stem cell niche, identifying small molecules for stem cell expansion in vitro, and recent developments in cell therapy, in particular islet cell transplant for treatment of diabetes. A major objective of the series continues to be to highlight timely, often emerging topics and novel approaches that can accelerate realizing the utility of stem cells in regenerative medicine. Amongst the latter is the use of zebrafish as a platform to screen drugs that regulate stem cell function. I remain very grateful to Gonzalo Cordova, the associate editor of the series, and wish to acknowledge his continued support. I would also like to acknowledge and thank Mariska van der Stigchel, Assistant Editor, for her outstanding efforts in helping to bring this volume to the production stages. A special thank you goes to Shanthi Ramamoorthy and Rathika Ramkumar for their outstanding efforts in the production of this volume.
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