Abstract
? 2022 Elsevier B.V.To reduce the risk of implant failure caused by “stress shielding” and bacterial infection, a porous Cu-bearing Ti-based BMG with high porosity (48.5%), hierarchical holes ranging from 0 to 600 μm in diameter and mechanical characteristics (162 MPa and 22.8 GPa) close to bone tissue was developed by a space holder method via SPS. With the aid of the space holder's size effect, the porosity and strength of the BMG have been further improved under the low Young's modulus without triggering the “stress shielding”. Furthermore, the addition of porous structures increases the rate of Cu ion release and significantly improves the antibacterial activity of the porous BMG without destroying biocompatibility. Taken together, the porous Ti-based BMG shows great potential as an ideal substitute for natural bone.
NSTL
Elsevier