Electrochemical oxidation chemoselective sulfimidation of thioether with sulfonamide via catalytic iodobenzene
Han, Min 1Tang, Zhuo 1Li, Guang-xun 1Wang, Qi-wei1
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作者信息
1. Chinese Acad Sci
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Abstract
Sulfilimines, the aza-analogs of sulfoxides, are valuable building blocks in organic synthesis and serve as important functional groups in medicinal chemistry. Herein we reported an efficient and environmen-tally friendly method of preparing sulfilimines from readily available thioether and sulfonamide as sub-strate. The reaction proceeds via the in-situ produced hypervalent iodine from catalytic simple iodobenzene under electrooxidation conditions. A series of sulfilimines were obtained in moderate to good yields.(c) 2022 Elsevier Ltd. All rights reserved.
NSTL
Elsevier