首页|Bisstyryl constituents from the leaves of Miliusa sinensis

Bisstyryl constituents from the leaves of Miliusa sinensis

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  • NSTL
  • Elsevier
? 2022 Phytochemical Society of EuropeMiliusa sinensis Finet and Gagnep. have recently been subjected to numerous scientific studies pursuing its structure and biological properties. The chromatographic separation of the components from the methanolic extract of M. sinensis leaves yielded three new bisstyryls, namely, sinenbisstyryls A–C (1–3). The structures of the new compounds were determined via interpretation of their spectroscopic data. Of the isolated compounds, sinenbisstyryl A (1) exhibited cytotoxic activity against the A549 human lung, HepG2 human hepatocyte carcinoma, MCF7 human breast, and DU145 human prostate cancer cell lines, with IC50 values of between 11.46 μM and 19.01 μM in four cases.

AnnonaceaeBisstyryl compoundCytotoxic activityMiliusa sinensisSinenbisstyryls A–C

Thi Hue C.、Hoa N.T.、Thi Hong P.、Trung V.T.、Binh P.T.、Van Thanh N.、Thao N.P.、Cuong N.T.

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Thuyloi University

Institute of Marine Biochemistry Vietnam Academy of Science and Technology (VAST)

Institute of Ecology and Biological Resources VAST

2022

10.1016/j.phytol.2022.03.012

Phytochemistry Letters

Phytochemistry Letters

SCI
ISSN：1874-3900
年,卷(期)：2022.49
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