首页|Geography and Time CONCEPTION in Pregnancy-Associated Stroke
Geography and Time CONCEPTION in Pregnancy-Associated Stroke
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NSTL
Lippincott Williams & Wilkins
Given the differences in the pattern of stroke in women, recent effort devoted to the acute management and prevention of stroke in women, 1may lead to the development of targeted prevention strategies. While young women have a low risk of stroke, it is higher than that for men of the same age. The risk in women escalates after the age of 65 years. Overall, women have a higher lifetime risk of stroke, likely explained by their longer lifespan. Strokes in pregnancy are fortunately rare, but given that maternal death from stroke occurred in 7.7% of cases, any studies aiming to identify prevention strategies or acute treatment leading to reduce this mortality are needed. At present, reperfusion (thrombolysis and thrombectomy) trials have excluded pregnant patients, and as such clinicians often do not offer these therapies to them. Recent observational studies have shown that reperfusion therapy is relatively safe in pregnant patients. Pregnant women have the same benefit from reperfusion therapy as non-pregnant women and men. In this issue of Neurology?, Martin et al. publish a prospective population-based study of pregnancy-associated stroke conducted over a 9-year period. The CONCEPTION study enrolled women with no history of stroke before pregnancy from France and other French overseas territories. These regions are linked by the French National Health Insurance Information System database, which contains data from all public and private hospital admissions. Unlike administrative database studies which rely on International Classification of Diseases, Ninth or Tenth Revision coding alone, the authors had access to the discharge summaries to verify the stroke diagnoses. The prevalence of stroke among more than million pregnant women was 0.02%.
Thanh G. Phan、Cheryl D. Bushnell、Henry Ma
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Stroke & Ageing Research, Department of Medicine, School of Clinical Sciences at Monash Health
NSTL
Lippincott Williams & Wilkins
