Medical hypotheses2021,Vol.1461.DOI:10.1016/j.mehy.2020.110365

Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis

Saadeldin, Mona Kamal Abdel-Aziz, Amal Kamal Abdellatif, Ahmed
Medical hypotheses2021,Vol.1461.DOI:10.1016/j.mehy.2020.110365

Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis

Saadeldin, Mona Kamal 1Abdel-Aziz, Amal Kamal 1Abdellatif, Ahmed2
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作者信息

  • 1. European Inst Oncol IRCCS, IEO, Dept Expt Oncol, I-20139 Milan, Italy
  • 2. Amer Univ Cairo, Dept Biol, Sch Sci & Engn, New Cairo 11835, Egypt
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Abstract

Immunotherapy is the newest approach to combat cancer. It can be achieved using several strategies, among which is the dendritic cell (DC) vaccine therapy. Several clinical trials are ongoing using DC vaccine therapy either as a sole agent or in combination with other interventions to tackle different types of cancer. Immunotherapy can offer a potential treatment to coronavirus disease 2019 (COVID-19) the worst pandemic facing this generation, a disease with deleterious effects on the health and economic systems worldwide. We hypothesize that DC vaccine therapy may provide a potential treatment strategy to help combat COVID-19. Cancer patients are at the top of the vulnerable population owing to their immune-compromised status. In this review, we discuss DC vaccine therapy in the light of the body's immunity, cancer, and newly emerging infections such as COVID-19 in hopes of better-customized treatment options for patients with multiple comorbidities.

Key words

Dendritic cell vaccine/Cancer/Immunotherapy/Combination therapy/Advantages/Disadvantages/COVID-19

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出版年

2021
Medical hypotheses

Medical hypotheses

SCI
ISSN:0306-9877
被引量8
参考文献量73
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