首页|Mitigation of marine toxins by interactions with bacteria: The case of okadaic acid and tetrodotoxin
Mitigation of marine toxins by interactions with bacteria: The case of okadaic acid and tetrodotoxin
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NSTL
Elsevier
Harmful algal bloom and marine toxins are actual and overgrowing problems. Okadaic acid (OA) is the main toxin responsible for diarrheic shellfish poisoning in humans, while Tetrodotoxin (TTX) is a tremendously strong neurotoxin. Given their high toxicity, strategies to obtain a mitigation of these toxins are every day more fundamental, in the optic of preserve consumer health, and in giving supports to shellfisheries in selling their products. In this context, the ability of lactic acid bacteria (LAB) and Paracoccus spp. to reduce OA and TTX in vitro was evaluated using HPLC/MS-MS technique. Different mechanisms of interaction were observed. Some species of LAB were able to reduce significantly the amount of toxin while in viable state (Lacticaseibacillus rhamnosus 1473 = 30% OA reduction), but also a binding effect of the toxins was observed. Contrarily, Paracoccus spp. was able to reduce significantly the amount of toxin while in a cell-free extract form, in particular Paracoccus aerius 5038 could reduce the presence of TTX of about 24%. This study provided a sound line of evidence for the possible future use of either specific bacteria or selected bacterial components to reduce the level of harmful marine toxins in aquaculture and food production.
NSTL
Elsevier
