首页|N-containing compounds from Hymenocallis littoralis and their cytotoxicity against Hep3B cells
N-containing compounds from Hymenocallis littoralis and their cytotoxicity against Hep3B cells
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NSTL
Elsevier
? 2022 Phytochemical Society of EuropeA chemical study focusing on the N-containing constituents of Hymenocallis littoralis was carried out, leading to the isolation of two new alkaloidal flavonoids (1–2) and five known alkaloids (3-7). Structures of the isolated compounds were established mainly by spectroscopic techniques, including NMR spectroscopy and mass spectrometry as well as the CD experiment. These compounds were subjected to the in vitro cytotoxicity assays using Hep3B cells, and among them only the known pancratistatine (3) and lycorine (5) could significantly inhibit the Hep3B cell proliferation.
Pang X.、Liu C.-Y.、Yu H.-Y.、Han L.-F.、Duan Z.-W.、Ma B.-P.
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State Key Laboratory of Component-Based Chinese Medicine Tianjin Key Laboratory of TCM Chemistry and Analysis Tianjin University of Traditional Chinese Medicine
Department of Pharmaceutical Sciences Beijing Institute of Radiation Medicine
NSTL
Elsevier
