首页|How do the alkaloids emetine and homoharringtonine kill trypanosomes? An insight into their molecular modes of action

How do the alkaloids emetine and homoharringtonine kill trypanosomes? An insight into their molecular modes of action

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  • NSTL
  • Elsevier
Background: Although Trypanosoma brucei causes deadly sleeping sickness, the number of the registered medications is rather limited. Some plant alkaloids are potent trypanocidal agents.

HomoharringtonineEmetineTrypanosomeProtein biosynthesisCell cycleMitochondrial membrane potential

Krstin, Sonja、Mohamed, Tamer、Wang, Xiaojuan、Wink, Michael

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Heidelberg Univ, Inst Pharm & Mol Biotechnol, Neuenheimer Feld 364, D-69120 Heidelberg, Germany

2016

10.1016/j.phymed.2016.10.008

Phytomedicine

Phytomedicine

SCI
ISSN：0944-7113
年,卷(期)：2016.23(14)
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