首页|Investigation of the permeability and optical clearing ability of different analytes in human normal and cancerous breast tissues by spectral domain OCT

Investigation of the permeability and optical clearing ability of different analytes in human normal and cancerous breast tissues by spectral domain OCT

扫码查看
原文链接
  • NSTL
  • Wiley
The potential of OCT applied for early breast cancer detection attracted significant efforts. The permeability coefficients and the percentages of OCT signal enhancement for normal and cancerous breast tissues have been investigated from the experiments of 20% glucose, 40% glucose, and 20% mannitol in vitro. Obtained results indicate that the permeability coefficient in breast cancer tissue is prominently larger than that in normal breast tissue, while the optical clearing effect is just the reverse to that for each agent. The results suggest that OCT has the ability to distinguish cancer tissue from different aspect. ((c) 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)

optical clearingpermeability coefficientbreast cancerglucosemannitoloptical coherence tomography

Zhu, Zhenguo、Wu, Guoyong、Wei, Huajiang、Yang, Hongqin、He, Yonghong、Xie, Shusen、Zhao, Qingliang、Guo, Xiao

展开 >

S China Normal Univ, MOE Key Lab Laser Life Sci, Guangzhou 510631, Guangdong, Peoples R China

Sun Yat Sen Univ, Affiliated Hosp 1, Dept Surg, Guangzhou 510080, Guangdong, Peoples R China

Fujian Normal Univ, Key Lab Optoelect Sci & Technol Med, Minist Educ China, Fuzhou 350007, Fujian, Peoples R China

Tsinghua Univ, Grad Sch Shenzhen, Shenzhen 518055, Guangdong, Peoples R China

展开 >

2012

10.1002/jbio.201100106

Journal of Biophotonics

Journal of Biophotonics

EISCI
ISSN：1864-063X
年,卷(期)：2012.5(7)
  • 12
  • 41