首页|CONSTITUENTS OF ESSENTIAL OIL FROM Vinca major var. variegata AND ITS ANTIBACTERIAL ACTIVITY
CONSTITUENTS OF ESSENTIAL OIL FROM Vinca major var. variegata AND ITS ANTIBACTERIAL ACTIVITY
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The genus Vinca is mainly native to Europe, southwest Asia, and northwest Africa [1]. Vinca major vox. variegata Loudon, belonging to Apocynaceae, is a Mediterranean species hemicryptophyte that is widely distributed in many European countries such as Romania, Austria, and Bulgaria and that grows on walls or cliffs [2]. V. major has been planted widely in China as a leaf-colored ornamental and functional plant [3]. The genus Vinca usually can be used to extract and isolate indole alkaloids with diverse structures for medicinal research and development [1]. There are some reports on the isolation of alkaloids of the leaves of V. major var. variegata, such as reserpinine, majdine, akuammicine, strictosidine lactam, seudoakuammigine, akuammine, 11-hydroxypolyneuridine, vallesiachotamine, isovallesiachotamine, reserpinine, vincamajine, and 10-hydroxycathofoline [4,5]. Majdine has antioxidant, apoptotic, and antiradical effects, and vallesiachotamine has [6] antiproliferative effects on human melanoma cells [7]. The alkaloid extract has high lipid peroxidation inhibitory, DPPH radical scavenging, and anticholinesterase activities.
Qiang Wei、Ruijie Liu
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School of Medicine, Anhui Xinhua University, 230088, Hefei, P. R. China
NSTL
