Medical hypotheses2021,Vol.1516.DOI:10.1016/j.mehy.2021.110586

Acute exercise and cognition: A review with testable questions for future research into cognitive enhancement with blood flow restriction

Yamada, Yujiro Frith, Emily M. Wong, Vickie Spitz, Robert W. Bell, Zachary W. Chatakondi, Raksha N. Abe, Takashi Loenneke, Jeremy P.
Medical hypotheses2021,Vol.1516.DOI:10.1016/j.mehy.2021.110586

Acute exercise and cognition: A review with testable questions for future research into cognitive enhancement with blood flow restriction

Yamada, Yujiro 1Frith, Emily M. 2Wong, Vickie 1Spitz, Robert W. 1Bell, Zachary W. 1Chatakondi, Raksha N. 1Abe, Takashi 1Loenneke, Jeremy P.1
扫码查看

作者信息

  • 1. Univ Mississippi, Dept Hlth Exercise Sci & Recreat Management, Kevser Ermin Appl Physiol Lab
  • 2. Penn State Univ, Dept Psychol, Cognit Neurosci Creat Lab, State Coll, PA 16801 USA
  • 折叠

Abstract

Blood flow restriction, in combination with low load/intensity exercise, has consistently been shown to increase both muscle size and strength. In contrast, the effects of blood flow restricted exercise on cognition have not been well studied. Therefore, the purpose of this paper is 1) to review the currently available literature investigating the impact of blood flow restricted exercise on cognition and 2) to provide some hypotheses for how blood flow restriction might provide an additive stimulus for augmenting specific cognitive domains above exercise alone. Given the lack of research in this area, the effects of blood flow restricted exercise on cognition are still unclear. We hypothesize that blood flow restricted exercise could potentially enhance several cognitive domains (such as attention, executive functioning, and memory) through increases in lactate production, catecholamine concentration, and PGC-1 alpha expression. We review work that suggests that blood flow restriction is not only a beneficial strategy to improve musculoskeletal function but could also be a favorable method for enhancing multiple domains of cognition. Nonetheless, it must be emphasized this is a hypothesis that currently has only minimal experimental support, and further investigations in the future are necessary to test the hypothesis.

Key words

Attention/Brain-derived neurotrophic factor/Executive function/Lactate/Memory

引用本文复制引用

出版年

2021
Medical hypotheses

Medical hypotheses

SCI
ISSN:0306-9877
被引量3
参考文献量64
段落导航相关论文