首页|Diverse acyclic diterpene derivatives from Aphanamixis sinensis

Diverse acyclic diterpene derivatives from Aphanamixis sinensis

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  • NSTL
  • Elsevier
Fifteen diterpene derivatives including seven new ones, sinensisins A-G (1, 2, 4, 7, 10, 14, 15), were obtained from the leaves and twigs of Aphanamixis sinensis. Their structures were elucidated by NMR spectroscopic and ECD data analyses. These diverse carbon skeletons containing meroditerpenoids, acyclic diterpenes, and norditerpenoids biogenetically were derived from chain-like diterpenes. Compounds 3, 5, and 6 showed inhibitory effects of nitric oxide (NO) production in LPS-induced RAW 264.7 cells.

Aphanamixis sinensisAcyclic diterpenesNO production inhibitoryDIMERSCONSTITUENTSPOLYSTACHYATERPENOIDSFRUITS

Cui, Letian、Cui, Zhirong、Wang, Zefan、Tang, Pengfei、Luo, Jun、Kong, Lingyi、Zhang, Panpan

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China Pharmaceut Univ

2022

10.1016/j.fitote.2022.105192

Fitoterapia

Fitoterapia

SCI
ISSN：0367-326X
年,卷(期)：2022.159
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