首页|Near-infrared spectroscopy during cardiopulmonary resuscitation for pediatric cardiac arrest: A prospective, observational study

Near-infrared spectroscopy during cardiopulmonary resuscitation for pediatric cardiac arrest: A prospective, observational study

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? 2022 Elsevier B.V.Aim: Cerebral oxygenation (rSO2) is not routinely measured during pediatric cardiopulmonary resuscitation (CPR). We aimed to determine whether higher intra-arrest rSO2 was associated with return of spontaneous circulation (ROSC) and survival to hospital discharge. Methods: Prospective, single-center observational study of cerebral oximetry using near-infrared spectroscopy (NIRS) during pediatric cardiac arrest from 2016 to 2020. Eligible patients had ≥30 s of rSO2 data recorded during CPR. We compared median rSO2 and percentage of rSO2 measurements above a priori thresholds for the entire event and the final five minutes of the CPR event between patients with and without ROSC and survival to discharge. Results: Twenty-one patients with 23 CPR events were analyzed. ROSC was achieved in 17/23 (73.9%) events and five/21 (23.8%) patients survived to discharge. The median rSO2 was higher for events with ROSC vs. no ROSC for the overall event (62% [56%, 70%] vs. 45% [35%, 51%], p = 0.025) and for the final 5 minutes of the event (66% [55%, 72%] vs. 43% [35%, 44%], p = 0.01). Patients with ROSC had a higher percentage of measurements above 50% during the final five minutes of CPR (100% [100%, 100%] vs. 0% [0%, 29%], p = 0.01). There was no association between rSO2 and survival to discharge. Conclusions: Higher cerebral rSO2 during CPR for pediatric cardiac arrest was associated with higher rates of ROSC but not with survival to discharge.

Cerebral oximetryNear-infrared spectroscopyPediatric cardiac arrestPediatric cardiopulmonary resuscitation

Francoeur C.、Landis W.P.、Winters M.、Naim M.Y.、Donoghue A.、Dominick C.L.、Huh J.W.、MacDonald J.M.、Lang S.S.、Yuan I.、Berg R.A.、Nadkarni V.M.、Kilbaugh T.J.、Sutton R.M.、Kirschen M.P.、Morgan R.W.、Topjian A.A.

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Department of Pediatrics CHU de Québec – Université Laval Research Center

Department of Anesthesiology and Critical Care Medicine Children's Hospital of Philadelphia

The Cardiac Center Children's Hospital of Philadelphia and The University of Pennsylvania Perelman

Department of Respiratory Therapy Children's Hospital of Philadelphia

Division of Pediatric Critical Care Medicine Nationwide Children's Hospital The Ohio State

Division of Neurosurgery Children's Hospital of Philadelphia

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2022

Resuscitation.

Resuscitation.

ISSN:0300-9572
年,卷(期):2022.174
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