首页|Salprzesides A and B: two novel icetexane diterpenes with antiangiogenic activity from Salvia przewalskii Maxim

Salprzesides A and B: two novel icetexane diterpenes with antiangiogenic activity from Salvia przewalskii Maxim

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Abstract Two novel icetexane diterpenes were isolated from Salvia przewalskii Maxim., namely Salprzesides A (1) and B (2), together with two known abietane-type diterpenes respectively identified as sahandinone (3) and miltirone (4). The structures of isolated compounds were determined by UV, IR, HR-ESI-MS, 1D and 2D NMR analysis. The in vitro antiangiogenic activities of compounds 1–4 were studied against human umbilical vascular endothelial cells (HUVECs). The IC50 values of compounds 1–4 ranged from 4.22?±?1.07 to 39.31?±?2.17?μM against HUVECs.

Salvia przewalskii Maxim.Salprzesides A and Bicetexane diterpenesantiangiogenic activity

Bei-Ming,Qiu、Pan,Wang、Jie,Li

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Department of Orthopaedics, The Second People’s Hospital of Yibin

2022

Natural product research

Natural product research

SCI
ISSN:1478-6419
年,卷(期):2022.36(10/12)
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