首页|Incidence, Clinical Characteristics, Risk Factors and Outcomes of Acute Coronary Syndrome in Patients With COVID-19: Results of the UMC-19-S10(10)

Incidence, Clinical Characteristics, Risk Factors and Outcomes of Acute Coronary Syndrome in Patients With COVID-19: Results of the UMC-19-S10(10)

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  • NSTL
  • Elsevier
Background: There is a lack of knowledge about the real incidence of acute coronary syndrome (ACS) in patients with COVID-19, their clinical characteristics, and their prognoses. Objective: We investigated the incidence, clinical characteristics, risk factors, and outcomes of ACS in patients with COVID-19 in the emergency department. Methods: We retrospectively reviewed all COVID-19 patients diagnosed with ACS in 62 Spanish emergency departments between March and April 2020 (the first wave of COVID-19). We formed 2 control groups: COVID-19 patients without ACS (control A) and non-COVID-19 patients with ACS (control B). Unadjusted comparisons between cases and control subjects were performed regarding 58 characteristics and outcomes. Results: We identified 110 patients with ACS in 74,814 patients with COVID-19 attending the ED (1.48% [95% confidence interval {CI} 1.21-1.78%]). This incidence was lower than that observed in non-COVID19 patients (3.64% [95% CI 3.54-3.74%]; odds ratio [OR] 0.40 [95% CI 0.33-0.49]). The clinical characteristics of patients with COVID-19 associated with a higher risk of presenting ACS were: previous coronary artery disease, age >= 60 years, hypertension, chest pain, raised troponin, and hypoxemia. The need for hospitalization and admission to intensive care and in-hospital mortality were higher in cases than in control group A (adjusted OR [aOR] 6.36 [95% CI 1.8422.1], aOR 4.63 [95% CI 1.88-11.4], and aOR 2.46 [95% CI 1.15-5.25]). When comparing cases with control group B, the aOR of admission to intensive care was 0.41 (95% CI 0.210.80), while the aOR for in-hospital mortality was 5.94 (95% CI 2.84-12.4). Conclusions: The incidence of ACS in patients with COVID-19 attending the emergency department was low, around 1.48%, but could be increased in some circumstances. Patients with COVID-19 with ACS had a worse prognosis than control subjects with higher in-hospital mortality. (C) 2021 Elsevier Inc. All rights reserved.

acute coronary syndromeclinical characteristicsCOVID-19incidenceoutcomerisk factorsSARS-Cov-2MYOCARDIAL-INFARCTIONEMERGENCY-DEPARTMENTSIMPACT

Alquezar-Arbe, Aitor、Miro, Oscar、Gonzalez del Castillo, Juan、Jimenez, Sonia、Llorens, Pere、Martin, Alfonso、Javier Martin-Sanchez, Francisco、de Simon Almela, Amparo Fernandez、Fortuny Bayarri, Maria Jose、Gonzalez Tejera, Matilde、Dominguez Rodriguez, Alberto、Burillo-Putze, Guillermo、Spanish Investigators Emergency Si、Jorge Garcia-Lamberechts, Eric、Pinera, Pascual、Jacob, Javier、Marin Porrino, Juan Miguel、Jimenez, Blas、del Rio, Rigoberto、Perez Garcia, Carles、Braso Aznar, Jose Vicente、Carmen Ponce, Maria、Diaz Fernandez, Elena、Tost, Josep、Martin Mojarro, Enrique、Huerta Garcia, Arturo、Martin Quiros, Alejandro、Noceda, Jose、Cano Cano, Maria Jose

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2022

10.1016/j.jemermed.2021.10.046

The Journal of Emergency Medicine

The Journal of Emergency Medicine

ISSN：0736-4679
年,卷(期)：2022.62(4)
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