Ancepsone A, a new sesterterpene with 13,19-epoxycheilanthane skeleton, i.e (17Z)-13,19-epoxy-cheilanth-1,17-diene-2-ol-3-one (1), together with eight known natural products (2 similar to 9) were isolated from Aleuritopteris anceps. The structure of the new compound was established by means of 1D and 2D NMR, MS, and single-crystal X-ray diffraction methods. All compounds were isolated from A. anceps for the first time. Ancepsone A and the isolated flavonoids can moderately inhibit the proliferation of cancer cells. (C) 2022 Elsevier Ltd. All rights reserved.
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