首页|THREE BIOACTIVE COMPOUNDS AGAINST COLONY FORMATION OF CHINESE HAMSTER V79 CELLS FROM AN INDONESIAN ASCIDIAN Didemnum sp.
THREE BIOACTIVE COMPOUNDS AGAINST COLONY FORMATION OF CHINESE HAMSTER V79 CELLS FROM AN INDONESIAN ASCIDIAN Didemnum sp.
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Marine invertebrates, such as sponges, ascidians, and soft corals, have been a rich source of bioactive chemical components with unique structural features [1,2]. Ascidians (tunicates) have provided a number of interesting compounds with marked bioactivities and peculiar structures, and, among them, ecteinascidin 743 has been utilized for the treatment of soft-tissue sarcomas [3]. The characteristic feature of structures isolated from ascidians is the high contents of the nitrogenous compounds [4], which are divided into two major groups, peptides (and amino acids) and alkaloids as ecteinascidins.
D. S. Wewengkang、H. Rotinsulu、D. A. Sumilat
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Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 981-8558, Sendai, Japan